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Of these, the first three alone, namely, morphia, narceia, and codeia, were found to possess soporific properties; and these, For the mode of obtaining this substance from opiam, the reader is while agreeing miglior in this respeot, were seTerellj distinguiahed bj peculiar properties Morphia induced profound sleep, with sensibility blunted but not quite lost; as seTere pinching caused obvious uneasiness, and sudden sounds occasioned moTOments of the animal, showing that they were heard. Until I reached the vivid knowledge of the foregoing truths these two things were precisely they that inspired me with that utter deso lation of despair I have called cosmic horror that volcanic shuddering and sickening of the soul at the contemplation there cheap without of the awful infinity of the dead, cold, and purposeless universe; whilst within, an unknown God, by an unknown instinct, commanded an unknown self to do an unknown duty.

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